PAK7KD (recombinant human PAK7 kinase domain, aka PAK5)
PAK7KD (PAK5KD) is a recombinant wild type human PAK7 kinase domain (amino acids 425–719 of full-length human PAK7) expressed in E. coli and purified to homogeneity with full activity. It is capable of promoting neurite outgrowth and cell survival.
Molecular Mass and Phosphorylation:
The calculated mass is 33,934. PAK7KD is fully phosphorylated at S602 and an additional site with a measured mass of 34,096 (2P).
Stability and Storage:
Stable at -70oC for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -70oC.
Enzymatic studies, inhibitor screen, and selectivity profiling
High concentration available for crystallization