PAK6KD (recombinant human PAK6 kinase domain)
PAK6KD is a recombinant wild type human PAK6 kinase domain (amino acids 385–680 of full-length human PAK6) expressed in E. coli and purified to homogeneity with full activity. PAK6 was found to interact with androgen receptor.
Molecular Mass and Phosphorylation:
The calculated mass is 34,161. PAK6KD is fully phosphorylated at S560 with a measured mass of 34,242 (1P).
Stability and Storage:
Stable at -70oC for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -70oC.
Enzymatic studies, inhibitor screen, and selectivity profiling
High concentration available for crystallization