Eton Bio Recombinant Human Acidic Fibroblast Growth Factor Intracellular-Binding Protein/FIBP is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp357) of Human FIBP.
Acidic Fibroblast Growth Factor Intracellular-Binding Protein (FIBP) is highly expressed in the heart, skeletal muscle, and pancreas. Acidic Fibroblast Growth Factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FIBP is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF.
|Names||Acidic Fibroblast Growth Factor Intracellular-Binding Protein, aFGF Intracellular-Binding Protein, FGF-1 Intracellular-Binding Protein, FIBP|
|Formulation||Supplied as a 0.2 μM filtered solution of 50mM Tris, pH 8.0|
|Shipping||The product is shipped on dry ice/ice packs.
|Storage||Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
|Purity||Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
|Endotoxin||Less than 0.1 ng/μg (1 IEU/μg).|
|Amino Acid Sequence||
AMADIGSMTSELDIFVGNTTLIDEDVYRLWLDGYSVTDAVALRVRSGILEQTGATAAVLQSDTMD HYRTFHMLERLLHAPPKLLHQLIFQIPPSRQALLIERYYAFDEAFVREVLGKKLSKGTKKDLDDI STKTGITLKSCRRQFDNFKRVFKVVEEMRGSLVDNIQQHFLLSDRLARDYAAIVFFANNRFETGK KKLQYLSFGDFAFCAELMIQNWTLGAVDSQMDDMDMDLDKEFLQDLKELKVLVADKDLLDLHKSL VCTALRGKLGVFSEMEANFKNLSRGLVNVAAKLTHNKDVRDLFVDLVEKFVEPCRSDHWPLSDVR FFLNQYSASVHSLDGFRHQALWDRYMGTLRGCLLRLYHD